ESR 10 vision / project
Exploring CD4+ T cells as carriers to mediate transport of drugs across the blood-brain barrier
Development of cell surface engineered CD4+ cells will allow the immobilization of drugs or drug carriers on the surface of CD4+ T cells. Study if surface-engineered CD4+ T cells are able to cross the BBB under flow in vitro and in vivo and if they can release drugs at the abluminal side
Protocols for the preparation of surface engineered T cells able to cross the BBB.
École Polytechnique Fédérale de Lausanne, Polymers Laboratory, Lausanne, Switzerland
Early Stage Researcher